Please use this identifier to cite or link to this item: http://hdl.handle.net/11328/3506
Title: Association study of variants in genes FTO, SLC6A4, DRD2, BDNF and GHRL with Binge Eating Disorder (BED) in Portuguese women
Authors: Palmeira, Lara
Cunha, Marina
Padez, Cristina
Alvarez, Manuela
Pinto-Gouveia, José
Manco, Licínio
Keywords: BED genetic susceptibility
FTO rs9939609 polymorphism
Obesity
Issue Date: Mar-2019
Publisher: Elsevier
Citation: Palmeira, L., Cunha, M., Padez, C., Alvarez, M., Pinto-Gouveia, J., & Manco, L. (2019). Association study of variants in genes FTO, SLC6A4, DRD2, BDNF and GHRL with binge eating disorder (BED) in Portuguese women. Psychiatry Research, 273, 309-311. Doi: 10.1016/j.psychres.2019.01.047. Disponível no Repositório UPT, http://hdl.handle.net/11328/3506
Abstract: A population based case-control study was conducted in Portuguese women with overweight/obesity to investigate the possible association of variants in genes FTO, SLC6A4, DRD2, BDNF and GHRL with binge eating disorder (BED). The distribution of seven polymorphisms was evaluated in 31 BED patients and 62 controls. No significant associations were found between polymorphisms and BED. Of interest, a markedly lower frequency of the FTO rs9939609 obesity risk A-allele was found in BED patients (0.290) in relation to the control group (0.402). Contrasting with anorexia nervosa and bulimia nervosa, our data suggest that rs9939609 A-allele has no potential role in BED.
URI: http://hdl.handle.net/11328/3506
ISSN: 0165-1781
Appears in Collections:INPP - Artigos em Revistas Internacionais / Papers in International Journals

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